Comics Alliance has been running a series of interviews with comic book retailers regarding the Orson Scott Card Superman thingie. I linked to the first one here. They've added parts two and three and four.
Part 2 is a conversation with the manager of Acme comics in North Carolina. It's a lot about how content can affect sales, but the manager ultimately believes his job is to give the choice to his customers, so he'll be stocking the comic in question. Even when he disagrees with the creator or content, it doesn't affect his business practices.
Jermaine Exum: Just like in the worlds of entertainment and sports, the comics
industry is not immune to creators who are divisive or are, in some
cases, difficult to support. The moment where a fan must decide if they
support the creation or the creator is never fun, nor is it anything you
can prepare for until it happens. I myself recently purged my personal
collection of the work of a creator I had previously enjoyed, due to his
outlook on the industry we are both part of and my interaction with him
at conventions. That creator's work is still on prominent display at
Acme Comics, and we reorder it regularly as needed.
In the third, with the owners of Challengers in Chicago, we learn that this store is planning on donating all their profits to the LGBT advocacy group called Human Rights Campaign. A couple of relevant passages:
Patrick Brower: It is never our intention to take the
choice away from the people who shop with us. Just because we may not be
fond of this particular creator's very public personal beliefs doesn't
mean fans of Superman that choose to shop at Challengers should be
denied the opportunity to get that issue of Adventures of Superman.
That we don't want to profit from it is not a good enough reason to not
let someone buy it if they want it. Also, that issue is an anthology
and Chris Samnee has work in that book. Have you seen his Superman
pin-up? It's gorgeous.